A 2-year postdoctoral position is available in the Biostatistics and Modeling group within the “Infection, Antimicrobials, Modeling & Evolution” research unit located in Paris, France (https://www.iame-research.center/eq4/research-interests/). Our group performs research in infectious diseases, with an emphasis on viral dynamics and immune system modeling. We develop mathematical and statistical models in collaboration with experimental virologists that generate new insights into the dynamics of viral infections and disease severity. We work with clinicians and pharmaceutical industry on the analysis of pre-clinical and clinical data, and we use pharmacometric models to understand drug’s mechanism of action in vivo, increase their antiviral activity and reduce virus pathogenesis. Our current work focuses on emerging viral infections, such as SARS-CoV-2, Monkeypox, and hemorrhagic fever viruses. Because inference is the most important limiting factor to the use of more physiological viral dynamic models, we also develop statistical methods to improve inference in non-linear mixed-effect models, in particular on model averaging and Bayesian methods.
The ideal candidate will have a PhD in applied mathematics or statistics, significant computational/programming skills (e.g. R, MatLab, C/C++) and strong interest in biomedical sciences and public health. Experience in working with experimental or clinical data and parameter estimation is desirable.
The position will be paid according to the INSERM salary guidelines (https://www.inserm.fr/en/home/). The position is available in January 2023, but flexibility on the starting date is possible. For initial consideration for this position and more details about the scientific areas of research, send an e-mail including your CV, a brief statement of interest and contact information for two academic references to jeremie.guedj@inserm.fr.